Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia
نویسندگان
چکیده
Low-risk human papillomavirus types 6 and 11 can manifest as giant condylomata acuminata (GCA) of Buschke-Lowenstein. Up to 50% of GCA can slowly progress over years to fungating, invasive tumors. The malignant potential is attributed to unique immune evading abilities of the human papillomavirus. A 42-year-old male presented with pain and foul-smelling discharge from his genital warts. The histopathological examination of the mass showed invasive squamous cell carcinoma, and it was associated with paraneoplastic hypercalcemia. The timely removal of long-standing GCA in order to prevent a carcinomatous transition is a priority.
منابع مشابه
Successful treatment of paraneoplastic hypercalcemia in a patient with giant condyloma acuminatum: a case report
INTRODUCTION While paraneoplastic syndromes in patients with malignant and metastasizing tumors are common, they are rarely associated with skin tumors showing predominantly local growth patterns. This case report relates to a patient with giant condyloma acuminatum, also called Buschke-Löwenstein tumor, with paraneoplastic hypercalcemia, who was successfully treated with conservative treatment...
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© 2015 The Authors. doi: 10.2340/00015555-1935 Journal Compilation © 2015 Acta Dermato-Venereologica. ISSN 0001-5555 Condylomata acuminata (CA) are sexually transmitted benign warty lesions that usually affect the anogenital epithelium. Low-risk human papillomavirus (HPV) infection, such as HPV type 6 or 11, is associated with the disease (1). These lesions exhibit a small papular, filiform or ...
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